Review Article

Non-melanoma Skin Cancer: Mini Review

Seyed Mohammad Amin Kormi , Shima Ardehkhani

Seyed Mohammad Amin Kormi
Cancer Genetics Research Unit, Reza Radiation Oncology Center, Mashhad, Iran. Email: Aminkormi@uoz.ac.ir

Shima Ardehkhani
Institute of Social Security & Welfare Applied Scientific Higher Education, Branch of Tehran, University of Science - Applied, Tehran, Iran.
Online First: March 29, 2017 | Cite this Article
Kormi, S., Ardehkhani, S. 2017. Non-melanoma Skin Cancer: Mini Review. The Cancer Press 3(1): 17-21. DOI:10.15562/tcp.40


Non-melanoma skin cancer (NMSC) has been frequently found in Caucasians. Basically, this type of cancer is divided into two parts, i.e. (BCC and SCC). Mutation in gene PTCH1 is one of the molecular causes involved in the disease process that plays an important role in the Sonic hedgehog signaling pathway, but the factors involving in the creation of NMCS are the ones such as age, exposure to UV ray, positive family history, male gender, genetic predisposition as well as skin color (Caucasians). In the therapeutic terms, surgery is considered as the best treatment although Radiotherapy and Cryotherapy are also used to treat but surgery is the gold standard of treatment. Immune therapy is also a new method of treatment for NMCS. In this paper, we have provided the treatment methods and have suggested the best treatment method through multiple studies. 

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